Understanding Encephalopathy: Part 2 - ICD-10 Coding Examples Definitions: Toxic Encephalopathy: A degenerative neurological disorder characterized by changes in mental status. It is caused by exposure to toxic substances or as an adverse effect of medication. Symptoms include memory loss, personality changes, lack of concentration, involuntary movements, nausea, fatigue, seizures, arm weakness, and depression. Anoxic Encephalopathy: Brain damage resulting from a lack of oxygen. Metabolic Encephalopathy: Temporary or permanent brain damage caused by various factors such as brain tumors, cerebral infarction or hemorrhage, cerebral ischemia, uremia, poisoning, systemic infection, and more. Symptoms can develop rapidly and may resolve when the underlying condition is treated. Coding Tips: The physician must explicitly document the diagnosis of encephalopathy for accurate coding. The type of encephalopathy cannot be assumed based solely on the definition. The physician's documentation ...